Basal forebrain neurons in the dementia of Parkinson disease
Identifieur interne : 002A94 ( Main/Exploration ); précédent : 002A93; suivant : 002A95Basal forebrain neurons in the dementia of Parkinson disease
Auteurs : Whitehouse [États-Unis] ; John C. Hedreen [États-Unis] ; Charles L. White Iii [États-Unis] ; Donald L. Price [États-Unis]Source :
- Annals of Neurology [ 0364-5134 ] ; 1983-03.
Abstract
Demented patients with Parkinson disease share certain neuropathological and neurochemical features with patients suffering from Alzheimer disease. Recently, loss of cholinergic neurons in the basal forebrain, particularly the nucleus basalis of Meynert, has been implicated in the pathophysiology of Alzheimer disease. The present investigation of 12 patients with Parkinson disease demonstrates that the demented patients with this disease also show a selective loss of cells in the nucleus basalis of Meynert, thus providing an important link between the dementias of Alzheimer disease and Parkinson disease.
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DOI: 10.1002/ana.410130304
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Recently, loss of cholinergic neurons in the basal forebrain, particularly the nucleus basalis of Meynert, has been implicated in the pathophysiology of Alzheimer disease. The present investigation of 12 patients with Parkinson disease demonstrates that the demented patients with this disease also show a selective loss of cells in the nucleus basalis of Meynert, thus providing an important link between the dementias of Alzheimer disease and Parkinson disease.</div></front></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>Maryland</li></region></list><tree><country name="États-Unis"><region name="Maryland"><name sortKey="Whitehouse" sort="Whitehouse" uniqKey="Whitehouse" last="Whitehouse">Whitehouse</name></region><name sortKey="Hedreen, John C" sort="Hedreen, John C" uniqKey="Hedreen J" first="John C." last="Hedreen">John C. Hedreen</name><name sortKey="Price, Donald L" sort="Price, Donald L" uniqKey="Price D" first="Donald L." last="Price">Donald L. Price</name><name sortKey="White Iii, Charles L" sort="White Iii, Charles L" uniqKey="White Iii C" first="Charles L." last="White Iii">Charles L. White Iii</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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